Pharma Science Monitor an International Journal of Pharmaceutical Sciences Formulation and Evaluation of Antimicrobial Polyherbal Cream
نویسنده
چکیده
Shree Swaminarayan Sanskar Pharmacy College, At & post Zundal, Ta. Dist. Gandhinagar-382 421. ABSTRACT Most of the antibiotics were originally derived from micro-organisms while the chemotherapeutic agents are from plants. Herbal medicine refers to the use of any plant's seeds, berries, roots, leaves, bark, Stem or flowers for medicinal purposes. Along with other dosage forms, herbal drugs are also formulated in the form of Cream formulation. Cream formulation is a viscous Semi-solid preparation used topically on a variety of body surfaces. The objective of the study was to formulate and evaluate the antimicrobial herbal semi solid formulation from the local medicinal plants. The ethanolic extracts of the selected plants and oils were taken in different ratio randomly and the antimicrobial tests of the combinations were carried out. The most effective combination was then determined by comparing the results of the zone of inhibition given by the 10 different extract ratios on Staphylococcus aureus, Pseudomonas aeruginosa and Candida albican species. Then the minimum inhibitory concentration of the each Plant extract and oils were found out. The Cream base was prepared and formulation of Cream was done by incorporating the active ingredients in most effective ratio in the base by trituration. After the completion of the formulation, quality of the Cream was assessed in terms of irritancy, pH , Viscosity , and stability.
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